Sergio Reguilón Rodríguez is a professional footballer who plays as a defender (left-back) for Premier League club Machester United on loan from Tottenham Hotspur. He also plays for the Spain national team. He was born in Madrid, Spain, and grew up in Collado Villalba.

A product of the youth system at the Bernabeu, Reguilón spent two separate spells on loan at Spanish Segunda División B side UD Logroñés between 2015 and 2017 before returning to become a regular for Real Madrid’s ‘Castilla’ second-string team, also in Segunda División B, in 2017/18, playing several games as their captain.

Reguilón made his first team debut for Real Madrid in October 2018 before earning his La Liga debut the following month and remained a regular member of their matchday squad during the 2018/19 season as Los Blancos won the FIFA Club World Cup. In July 2019, he was loaned to Sevilla for the 2019–20 season.

Reguilón joined Tottenham Hotspur from Real Madrid in September 2020. In August 2022, he joined La Liga side Atletico Madrid on loan for the 2022/23 campaign.

At the international level, Reguilón has represented Spain at under-21 and senior levels. His performances during the 2019/20 season earned him a first call-up for the Spanish national team in October 2019, and he made his senior international debut in September 2020.